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Short description:
Please summarise the application in a few sentences. Avoid links here. ConDeTri is a content dependent read trimming software for Illumina/Solexa sequencing data
Software version:
Biological application domain(s) (Phylogenetics, Genomics, ...):
RNA-Seq, Sequencing, Genomics,
Principal bioinformatics method(s) (Assembly, Mapping, ...):
Sequence trimming,
Technology (Sanger, Illumina, 454, SOLiD, Ion Torrent, ...):
Illumina
Interface (Command line, Web UI, Desktop GUI, SOAP WS, HTTP WS, API, QL):
Resource type (Command-line tool, Web application, Desktop application, Script, Suite, Workbench, Database portal, Workflow, Plug-in, Library, Web API, Web service, SPARQL endpoint):
== Description == <!-- Describe the application in the space below --> During the last few years, DNA and RNA sequencing have become to play a more important role in biological and medical applications, especially due to the increasing amount of sequencing data yield from the sequencing machines and the enormous drop down of sequencing costs. Particularly, Illumina sequencing has an increasing impact on gathering data from model and non-model organisms. However, accurate and easy to use tools for quality filtering have not yet been established. We present ConDeTri, a method for content dependent read trimming for Illumina data using quality scores of each base individually. It is independent from sequencing coverage and user interaction. The main focus of the implementation is on usability and to incorporate read trimming in next-generation sequencing data processing and analysis pipelines. It can process single-end and paired-end sequencing data of arbitrary length. ConDeTri is able to trim and remove reads with low quality scores to get better results from de novo assemblies. Especially, low coverage or large genome sequencing projects gain from trimming reads. <!-- -->
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