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Short description:
Please summarise the application in a few sentences. Avoid links here. User-friendly tools for the normalization and visualization of deep-sequencing data.
Software version:
Biological application domain(s) (Phylogenetics, Genomics, ...):
Genomics, ChIP-seq,
Principal bioinformatics method(s) (Assembly, Mapping, ...):
Standardisation and normalisation, Visualisation, Conversion,
Technology (Sanger, Illumina, 454, SOLiD, Ion Torrent, ...):
Illumina HiSeq, 454, Illumina,
Interface (Command line, Web UI, Desktop GUI, SOAP WS, HTTP WS, API, QL):
Resource type (Command-line tool, Web application, Desktop application, Script, Suite, Workbench, Database portal, Workflow, Plug-in, Library, Web API, Web service, SPARQL endpoint):
deepTools is maintained by the Bioinformatics and Deep-Sequencing Unit at the Max Planck Institute of Immunobiology and Epigenetics.
== Description == <!-- Describe the application in the space below --> deepTools addresses the challenge of handling the large amounts of data that are now routinely generated from DNA sequencing centers. To do so, deepTools contains useful modules to process the mapped reads data to create coverage files in standard bedGraph and bigWig file formats. By doing so, deepTools allows the creation of normalized coverage files or the comparison between two files (for example, treatment and control). Finally, using such normalized and standardized files, multiple visualizations can be created to identify enrichments with functional annotations of the genome. For a gallery of images that can be produced, see http://f1000.com/posters/browse/summary/1094053 <!-- -->
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