You do not have permission to edit this page, for the following reason:
The action you have requested is limited to users in the group: Users.
Short description:
Please summarise the application in a few sentences. Avoid links here. SRMA is a short read micro re-aligner for next-generation high throughput sequencing data.
Software version:
Biological application domain(s) (Phylogenetics, Genomics, ...):
SNP detection, Indel detection
Principal bioinformatics method(s) (Assembly, Mapping, ...):
Localised reassembly
Technology (Sanger, Illumina, 454, SOLiD, Ion Torrent, ...):
Illumina, ABI SOLiD, 454
Interface (Command line, Web UI, Desktop GUI, SOAP WS, HTTP WS, API, QL):
Resource type (Command-line tool, Web application, Desktop application, Script, Suite, Workbench, Database portal, Workflow, Plug-in, Library, Web API, Web service, SPARQL endpoint):
University of California, Los Angeles
== Description == SRMA is a short read micro re-aligner for next-generation high throughput sequencing data. Sequence alignment algorithms examine each read independently. When indels occur towards the ends of reads, the alignment can lead to false SNPs as well as improperly placed indels. This tool aims to perform a re-alignment of each read to a graphical representation of all alignments within a local region to provide a better overall base-resolution consensus. Currently this tool works well with and has been tested on 30x diploid coverage genome sequencing data from Illumina and ABI SOLiD technology. This tool may not work well with 454 data, as indels are a significant error mode for 454 data.
Once you save the form, you will have the chance to add links and references.
Summary of edit
This is a minor edit Watch this page
Cancel