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MUMmer

40 bytes added, 16:06, 19 December 2015
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Text replace - "Alignment" to "Sequence alignment"
|sw summary=MUMmer is a modular system for the rapid whole genome alignment of finished or draft sequence. Basically it is a ultra-fast alignment of large-scale DNA and protein sequences
|bio domain=Genomics, Transcriptomics,
|bio method=AlignmentSequence alignment, MappingRead mapping,
|bio tech=Any
|created by=Kurtz S, Phillippy A, Delcher AL, Smoot M, Shumway M, Antonescu C, Salzberg SL
|os=Linux,
}}
[http://www.ncbi.nlm.nih.gov/pubmed/19389736 This paper] claims to be interface equivalent, and more memory efficient. See http://compbio.cs.princeton.edu/mems
 
MUMmer is released as a package providing an efficient suffix tree library, seed-and-extend alignment, SNP detection, repeat detection, and visualization tools.
MUMmer is a system for rapidly aligning entire genomes, whether in complete or draft form. For example, MUMmer 3.0 can find all 20-basepair or longer exact matches between a pair of 5-megabase genomes in 13.7 seconds, using 78 MB of memory, on a 2.4 GHz Linux desktop computer. MUMmer can also align incomplete genomes; it can easily handle the 100s or 1000s of contigs from a shotgun sequencing project, and will align them to another set of contigs or a genome using the NUCmer program included with the system. If the species are too divergent for a DNA sequence alignment to detect similarity, then the PROmer program can generate alignments based upon the six-frame translations of both input sequences. The original MUMmer system, version 1.0, is described in our 1999 Nucleic Acids Research paper. Version 2.1 appeared a few years later and is described in our 2002 Nucleic Acids Research paper, while MUMmer 3.0 was recently described in our 2004 Genome Biology paper.
 
[http://www.ncbi.nlm.nih.gov/pubmed/19389736 This paper] by another research group claims to be interface equivalent, and more memory efficient. See http://compbio.cs.princeton.edu/mems