Difference between revisions of "ChIPmeta"

From SEQwiki
Jump to: navigation, search
 
(9 intermediate revisions by 3 users not shown)
Line 1: Line 1:
 
{{Bioinformatics application
 
{{Bioinformatics application
|sw summary=In this work, hierarchical hidden Markov model (HHMM) is proposed for combining data from ChIP-seq and ChIP-chip. In HHMM, inference results from individual HMMs in ChIP-seq and ChIP-chip experiments are summarized by a higher level HMM. Simulation studies show the advantage of HHMM when data from both technologies co-exist. Analysis of two well-studied transcription factors, NRSF and CTCF, also suggests that HHMM yields improved TFBS identification in comparison to analyses using individual data sources or a simple merger of the two.
+
|sw summary=Combining data from ChIP-seq and ChIP-chip.
|bio domain=ChIPseq
+
|bio domain=Transcription factors and regulatory sites, ChIP-seq, ChIP-on-chip,
 +
|bio method=Peak calling,
 +
|interface= Command line
 +
|resource type=Command-line tool,
 
}}
 
}}
 +
In HHMM, inference results from individual HMMs in ChIP-seq and ChIP-chip experiments are summarized by a higher level HMM. Simulation studies show the advantage of HHMM when data from both technologies co-exist. Analysis of two well-studied transcription factors, NRSF and CTCF, also suggests that HHMM yields improved TFBS identification in comparison to analyses using individual data sources or a simple merger of the two.
 +
{{Links}}
 +
{{References}}
 +
{{Link box}}

Latest revision as of 12:11, 3 November 2016

Application data

Biological application domain(s) Transcription factors and regulatory sites, ChIP-seq, ChIP-on-chip
Principal bioinformatics method(s) Peak calling
Maintained? Maybe
Interface type(s) Command line
Resource type(s) Command-line tool

Summary: Combining data from ChIP-seq and ChIP-chip.

"Error: no local variable "counter" was set." is not a number.

In HHMM, inference results from individual HMMs in ChIP-seq and ChIP-chip experiments are summarized by a higher level HMM. Simulation studies show the advantage of HHMM when data from both technologies co-exist. Analysis of two well-studied transcription factors, NRSF and CTCF, also suggests that HHMM yields improved TFBS identification in comparison to analyses using individual data sources or a simple merger of the two.

Links


References

  1. . 2009. Bioinformatics


To add a reference for ChIPmeta, enter the PubMed ID in the field below and click 'Add'.

 


Search for "ChIPmeta" in the SEQanswers forum / BioStar or:

Web Search Wiki Sites Scientific