Difference between revisions of "Sibelia"
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{{Bioinformatics application | {{Bioinformatics application | ||
|sw summary=Sibelia: A comparative genomic tool: It assists biologists in analysing the genomic variations that correlate with pathogens, or the genomic changes that help microorganisms adapt in different environments. Sibelia will also be helpful for the evolutionary and genome rearrangement studies for multiple strains of microorganisms. | |sw summary=Sibelia: A comparative genomic tool: It assists biologists in analysing the genomic variations that correlate with pathogens, or the genomic changes that help microorganisms adapt in different environments. Sibelia will also be helpful for the evolutionary and genome rearrangement studies for multiple strains of microorganisms. | ||
| − | |bio domain=Genomics, | + | |bio domain=Genomics, |
| − | |bio method=Variant | + | |bio method=Variant calling, |
|created by=Ilya Minkin, Nikolay Vyahhi, Son Pham | |created by=Ilya Minkin, Nikolay Vyahhi, Son Pham | ||
|created at=Academic University, Russia | |created at=Academic University, Russia | ||
Latest revision as of 10:24, 25 August 2015
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Application data |
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| Created by | Ilya Minkin, Nikolay Vyahhi, Son Pham |
|---|---|
| Biological application domain(s) | Genomics |
| Principal bioinformatics method(s) | Variant calling |
| Created at | Academic University, Russia |
| Maintained? | Yes |
| Input format(s) | FASTA |
| Programming language(s) | C++ |
| Licence | GPL |
Summary: Sibelia: A comparative genomic tool: It assists biologists in analysing the genomic variations that correlate with pathogens, or the genomic changes that help microorganisms adapt in different environments. Sibelia will also be helpful for the evolutionary and genome rearrangement studies for multiple strains of microorganisms.
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Description
Sibelia is useful in finding:
- shared regions,
- regions that present in one group of genomes but not in others,
- rearrangements that transform one genome to other genomes.
In version 2, Sibelia works with multiple strains of bacteria and partitions their genomes into synteny blocks — blocks of highly conserved regions among all compared genomes. It represents genomes in circos pictures [for publication] or interactive forms [for experts’ analysis].
Links
References
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