Difference between revisions of "GenomicTools"

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(Created page with "{{Bioinformatics application |sw summary=GenomicTools is a flexible computational platform for the analysis and manipulation of high-throughput sequencing data such as RNA-seq an...")
 
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{{Bioinformatics application
 
{{Bioinformatics application
|sw summary=GenomicTools is a flexible computational platform for the analysis and manipulation of high-throughput sequencing data such as RNA-seq and ChIP-seq. A variety of mathematical operations between sets of genomic regions is implemented thereby enabling the prototyping of computational pipelines that can address a wide spectrum of tasks from preprocessing and quality control to meta-analyses. More specifically, the user can easily create average read profiles across transcriptional start sites or enhancer sites, quickly prototype customized peak discovery methods for ChIP-seq experiments, perform genome-wide statistical tests such as enrichment analyses, design controls via appropriate randomization schemes, among other applications.  
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|sw summary=GenomicTools is a flexible computational platform for the analysis and manipulation of high-throughput sequencing data such as RNA-seq and ChIP-seq. A variety of mathematical operations between sets of genomic regions is implemented thereby enabling the prototyping of computational pipelines that can address a wide spectrum of tasks from preprocessing and quality control to meta-analyses. More specifically, the user can easily create average read profiles across transcriptional start sites or enhancer sites, quickly prototype customized peak discovery methods for ChIP-seq experiments, perform genome-wide statistical tests such as enrichment analyses, design controls via appropriate randomization schemes, among other applications.
|bio domain=Genomics, ChIP-Seq, RNA-Seq,  
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|bio domain=Genomics, ChIP-Seq, RNA-Seq,
|bio method=genomic overlaps, Peak detection, profiles, heatmaps
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|bio method=genomic overlaps, peak detection, profiles, heatmaps
 
|created by=Aristotelis Tsirigos
 
|created by=Aristotelis Tsirigos
 
|created at=IBM Research
 
|created at=IBM Research
 
|maintained=Yes
 
|maintained=Yes
|input format=BED, SAM/BAM, GFF,  
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|input format=BED, SAM/BAM, GFF,
 
|output format=BED, SAM, GFF
 
|output format=BED, SAM, GFF
|sw feature=Create custom pipelines, Feature overlaps, Identify binding site peaks in ChIP-Seq data, Create read profiles, Create read heatmaps
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|sw feature=create custom pipelines, feature overlaps, identify binding site peaks in ChIP-seq data, create read profiles, create read heatmaps
 
|language=C/C++
 
|language=C/C++
|licence=GPL 2,  
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|licence=GPL 2,
 
}}
 
}}
 
== Description ==
 
== Description ==

Revision as of 15:06, 13 April 2012

Application data

Created by Aristotelis Tsirigos
Biological application domain(s) Genomics, ChIP-Seq, RNA-Seq
Principal bioinformatics method(s) genomic overlaps, peak detection, profiles, heatmaps
Created at IBM Research
Maintained? Yes
Input format(s) BED, SAM/BAM, GFF
Output format(s) BED, SAM, GFF
Software features create custom pipelines, feature overlaps, identify binding site peaks in ChIP-seq data, create read profiles, create read heatmaps
Programming language(s) C/C++
Licence GPL 2

Summary: GenomicTools is a flexible computational platform for the analysis and manipulation of high-throughput sequencing data such as RNA-seq and ChIP-seq. A variety of mathematical operations between sets of genomic regions is implemented thereby enabling the prototyping of computational pipelines that can address a wide spectrum of tasks from preprocessing and quality control to meta-analyses. More specifically, the user can easily create average read profiles across transcriptional start sites or enhancer sites, quickly prototype customized peak discovery methods for ChIP-seq experiments, perform genome-wide statistical tests such as enrichment analyses, design controls via appropriate randomization schemes, among other applications.

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Description

Links


References

  1. . 2012. Bioinformatics


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