Difference between revisions of "GenomicTools"
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{{Bioinformatics application | {{Bioinformatics application | ||
− | |sw summary=GenomicTools is a flexible computational platform for the analysis and manipulation of high-throughput sequencing data such as RNA-seq and ChIP-seq. A variety of mathematical operations between sets of genomic regions is implemented thereby enabling the prototyping of computational pipelines that can address a wide spectrum of tasks from preprocessing and quality control to meta-analyses. More specifically, the user can easily create average read profiles across transcriptional start sites or enhancer sites, quickly prototype customized peak discovery methods for ChIP-seq experiments, perform genome-wide statistical tests such as enrichment analyses, design controls via appropriate randomization schemes, among other applications. | + | |sw summary=GenomicTools is a flexible computational platform for the analysis and manipulation of high-throughput sequencing data such as RNA-seq and ChIP-seq. A variety of mathematical operations between sets of genomic regions is implemented thereby enabling the prototyping of computational pipelines that can address a wide spectrum of tasks from preprocessing and quality control to meta-analyses. More specifically, the user can easily create average read profiles across transcriptional start sites or enhancer sites, quickly prototype customized peak discovery methods for ChIP-seq experiments, perform genome-wide statistical tests such as enrichment analyses, design controls via appropriate randomization schemes, among other applications. |
− | |bio domain=Genomics, ChIP-Seq, RNA-Seq, | + | |bio domain=Genomics, ChIP-Seq, RNA-Seq, |
− | |bio method=genomic overlaps, | + | |bio method=genomic overlaps, peak detection, profiles, heatmaps |
|created by=Aristotelis Tsirigos | |created by=Aristotelis Tsirigos | ||
|created at=IBM Research | |created at=IBM Research | ||
|maintained=Yes | |maintained=Yes | ||
− | |input format=BED, SAM/BAM, GFF, | + | |input format=BED, SAM/BAM, GFF, |
|output format=BED, SAM, GFF | |output format=BED, SAM, GFF | ||
− | |sw feature= | + | |sw feature=create custom pipelines, feature overlaps, identify binding site peaks in ChIP-seq data, create read profiles, create read heatmaps |
|language=C/C++ | |language=C/C++ | ||
− | |licence=GPL 2, | + | |licence=GPL 2, |
}} | }} | ||
== Description == | == Description == |
Revision as of 15:06, 13 April 2012
Application data |
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Created by | Aristotelis Tsirigos |
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Biological application domain(s) | Genomics, ChIP-Seq, RNA-Seq |
Principal bioinformatics method(s) | genomic overlaps, peak detection, profiles, heatmaps |
Created at | IBM Research |
Maintained? | Yes |
Input format(s) | BED, SAM/BAM, GFF |
Output format(s) | BED, SAM, GFF |
Software features | create custom pipelines, feature overlaps, identify binding site peaks in ChIP-seq data, create read profiles, create read heatmaps |
Programming language(s) | C/C++ |
Licence | GPL 2 |
Summary: GenomicTools is a flexible computational platform for the analysis and manipulation of high-throughput sequencing data such as RNA-seq and ChIP-seq. A variety of mathematical operations between sets of genomic regions is implemented thereby enabling the prototyping of computational pipelines that can address a wide spectrum of tasks from preprocessing and quality control to meta-analyses. More specifically, the user can easily create average read profiles across transcriptional start sites or enhancer sites, quickly prototype customized peak discovery methods for ChIP-seq experiments, perform genome-wide statistical tests such as enrichment analyses, design controls via appropriate randomization schemes, among other applications.
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