Kmergenie

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Application data

Created by R. Chikhi, P. Medvedev
Biological application domain(s) Genomic Assembly
Principal bioinformatics method(s) Assembly
Technology Illumina
Created at Penn State University
Maintained? Yes
Input format(s) Fasta/Fastq
Output format(s) HTML report
Programming language(s) C++/Python/R

Summary: KmerGenie estimates the best k-mer length for genome de novo assembly. Given a set of reads, KmerGenie first computes the k-mer abundance histogram for many values of k. Then, for each value of k, it predicts the number of distinct genomic k-mers in the dataset, and returns the k-mer length which maximizes this number. Experiments show that KmerGenie's choices lead to assemblies that are close to the best possible over all k-mer lengths.

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