Methpipe

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Application data

Created by Qiang Song, et al
Biological application domain(s) Epigenomics, DNA methylation, Bisulfite Sequencing
Principal bioinformatics method(s) Bisulfite mapping, Analysis Pipeline
Technology Illumina
Created at University of Southern California
Maintained? Yes
Input format(s) FASTQ, SAM/BAM
Programming language(s) C++
Licence GPL (>= 3)
Operating system(s) Linux, Mac OS X
Contact: methpipe@googlegroups.com

Summary: The MethPipe software package is a computational pipeline for analyzing bisulfite sequencing data (BS-seq, WGBS and RRBS). MethPipe provides tools for mapping bisulfite sequencing read and estimating methylation levels at individual cytosine sites. Additionally, MethPipe includes tools for identifying higher-level methylation features, such as hypo-methylated regions (HMR), partially methylated domains (PMD), hyper-methylated regions (HyperMR), and allele-specific methylated regions (AMR).

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Description

Links


References

  1. . 2013. PLoS One


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