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Short description:
Please summarise the application in a few sentences. Avoid links here. CLEVER is a tool to discover structural variations such as (larger) insertions and deletions in genomes from paired-end sequencing reads.
Software version:
Biological application domain(s) (Phylogenetics, Genomics, ...):
Genomics, Structural variation, Copy number estimation
Principal bioinformatics method(s) (Assembly, Mapping, ...):
Technology (Sanger, Illumina, 454, SOLiD, Ion Torrent, ...):
Any, Illumina,
Interface (Command line, Web UI, Desktop GUI, SOAP WS, HTTP WS, API, QL):
Resource type (Command-line tool, Web application, Desktop application, Script, Suite, Workbench, Database portal, Workflow, Plug-in, Library, Web API, Web service, SPARQL endpoint):
CWI Amsterdam
== Description == <!-- Describe the application in the space below --> CLEVER (CLique Enumerating Variant findER) is an internal segment size based approach, which organizes all reads (including concordant ones) into a read alignment graph where max-cliques represent maximal contradiction-free groups of alignments. A specifically engineered algorithm then enumerates all max-cliques and statistically evaluates them for their potential to reflect insertions or deletions (indels). <!-- -->
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