Difference between revisions of "FreClu"
m (Text replace - "([= ])[Mm]apping," to "$1Read mapping,") |
m (Text replace - "RNA-Seq Alignment" to "RNA-Seq alignment") |
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{{Bioinformatics application | {{Bioinformatics application | ||
|sw summary=a frequency-based, de novo short-read clustering method that organizes erroneous short sequences originating in a single abundant sequence into a tree structure; in this structure, each “child” sequence is considered to be stochastically derived from its more abundant “parent” sequence with one mutation through sequencing errors. The root node is the most frequently observed sequence that represents all erroneous reads in the entire tree, allowing the alignment of the reliable representative read to the genome without the risk of mapping erroneous reads to false-positive positions. | |sw summary=a frequency-based, de novo short-read clustering method that organizes erroneous short sequences originating in a single abundant sequence into a tree structure; in this structure, each “child” sequence is considered to be stochastically derived from its more abundant “parent” sequence with one mutation through sequencing errors. The root node is the most frequently observed sequence that represents all erroneous reads in the entire tree, allowing the alignment of the reliable representative read to the genome without the risk of mapping erroneous reads to false-positive positions. | ||
| − | |bio domain=RNA-Seq | + | |bio domain=RNA-Seq alignment |
|bio method=Read mapping, | |bio method=Read mapping, | ||
}} | }} | ||
Latest revision as of 18:55, 2 December 2015
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Application data |
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| Biological application domain(s) | RNA-Seq alignment |
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| Principal bioinformatics method(s) | Read mapping |
| Maintained? | Maybe |
Summary: a frequency-based, de novo short-read clustering method that organizes erroneous short sequences originating in a single abundant sequence into a tree structure; in this structure, each “child” sequence is considered to be stochastically derived from its more abundant “parent” sequence with one mutation through sequencing errors. The root node is the most frequently observed sequence that represents all erroneous reads in the entire tree, allowing the alignment of the reliable representative read to the genome without the risk of mapping erroneous reads to false-positive positions.
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