Difference between revisions of "SeqMan NGen"

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{{Bioinformatics application
 
{{Bioinformatics application
 
|sw summary=Sequence assembly software using traditional, next-gen, and third-gen techonologies. Subsequent analysis of the assembly, including SNP discovery, coverage evaluation and consensus annotation is provided through full integration with Lasergene.
 
|sw summary=Sequence assembly software using traditional, next-gen, and third-gen techonologies. Subsequent analysis of the assembly, including SNP discovery, coverage evaluation and consensus annotation is provided through full integration with Lasergene.
|sw logo=ProdLogo NG pp.png
 
 
|bio domain=Genomics, De-novo assembly, De novo transcriptome assembly, Whole Genome Resequencing, SNP discovery, InDel discovery, ChIP-Seq, RNA-Seq Alignment
 
|bio domain=Genomics, De-novo assembly, De novo transcriptome assembly, Whole Genome Resequencing, SNP discovery, InDel discovery, ChIP-Seq, RNA-Seq Alignment
 
|bio method=Mapping, Assembly, Alignment, Paired End
 
|bio method=Mapping, Assembly, Alignment, Paired End

Revision as of 16:45, 19 May 2011

Application data

Biological application domain(s) Genomics, De-novo assembly, De novo transcriptome assembly, Whole Genome Resequencing, SNP discovery, InDel discovery, ChIP-Seq, RNA-Seq Alignment
Principal bioinformatics method(s) Mapping, Assembly, Alignment, Paired End
Technology IonTorrent, 454, Illumina, ABI SOLiD, Helicos, Sanger
Created at http://www.DNASTAR.com
Maintained? Yes
Input format(s) FASTA, FASTQ, Scarf, SFF, SQD, ACE, PHD, ABI, AB1, GFF, CSFASTA/CSQUAL (ABI SOLiD), SCF, TXT, GenBank, SEQ
Output format(s) BAM, SAM, SQD, ACE, FASTA
Licence Available as a standalone system or as a network license.
Operating system(s) Windows, Mac OS X, Linux

Summary: Sequence assembly software using traditional, next-gen, and third-gen techonologies. Subsequent analysis of the assembly, including SNP discovery, coverage evaluation and consensus annotation is provided through full integration with Lasergene.

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SeqMan NGen® is next-gen sequence assembly software that uses a patented algorithm to provide fast and accurate sequence assembly of data from all major next-gen and third-gen platforms, including Illumina, Roche 454, SOLiD, and Ion Torrent. SeqMan NGen represents a breakthrough in sequence assembly software as it has the ability to assemble human and other large eukaryotic genomes against a genomic template quickly and easily on a desktop computer. Optimized assembly parameter settings are automatically determined for you, based on your read technology and your specific project objective, such as genome assembly, targeted resequencing, and de novo transcriptome workflows.

SeqMan NGen is fully integrated with Lasergene's SeqMan Pro, so that once your assembly is complete, numerous tools are available for analyzing your project, including SNP and genotype calling using Bayesian statistical models, direct comparison to dbSNP, evaluating coverage, and annotating your consensus sequence.

The most recent version of SeqMan NGen is 3.0, which was initially released as a beta version in December 2010, and subsequently officially released in February 2011.

Links


References

  1. . 2010. BMC Genomics
  2. . 2011. BMC Genomics
  3. . 2012. BMC Genomics
  4. . 2012. PNAS
  5. . 2012. Journal of Bacteriology
  6. . 2012. Systematic biology
  7. . 2012. Microbiology
  8. . 2012. Proceedings: Biological Sciences / The Royal Society
  9. . 2012. Clinical and Vaccine Immunology
  10. . 2012. Journal of Bacteriology
  11. . 2012. PLoS One
  12. . 2012. Journal of Bacteriology
  13. . 2012. Applied Environmental Microbiology
  14. . 2012. Journal of Bacteriology
  15. . 2013. Genetics
  16. . 2013. Applied and Environmental Microbiology
  17. . 2013. Genome biology and evolution


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