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Application data |
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| Biological application domain(s) | Targeted resequencing |
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| Created at | Charité-Universitätsmedizin Berlin |
| Maintained? | Maybe |
| Programming language(s) | R, Java |
Summary: Our algorithm uses a non-homogeneous hidden Markov model (HMM) that employs local recombination rates to identify chromosomal regions that are identical by descent (IBD=2) in children of consanguineous or non-consanguineous parents solely based on genotype data of siblings derived from high-throughput sequencing platforms.
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