MirTools
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Application data |
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| Created by | Jinyu Wu |
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| Biological application domain(s) | small RNA transcriptome |
| Technology | Solexa, 454 |
| Created at | Institute of Genomic Medicine, Wenzhou Medical College, Wenzhou 325035, China |
| Maintained? | Yes |
| Input format(s) | Short read tag with count |
| Output format(s) | Detailed annotation |
| Programming language(s) | Perl, PHP |
Summary: web server for microRNA profiling and discovery based on high-throughput sequencing
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a comprehensive web server mirTools was developed to allow researchers to comprehensive characterizes the small RNA transcriptome. With the aid of mirTools, it can: 1) Align the large-scale short reads to the reference genome and exhibit the length distribution; 2) Classify of the large-scale short reads into known categories, such as known miRNAs, non-coding RNA, genomic repeats or coding sequences; 3) Provide detailed annotation information of known miRNAs, such as miRNA/miRNA*, absolute/relative reads count and the most abundant tag; 4) Discovery of the novel miRNAs that have not been characterized before from the large-scale short reads; 5) Identify of the differentially expressed miRNAs between samples according to different count strategies, such as total read tag counts and the most abundant tag of specific miRNA.
