MACS

Application data
Maintained?	Maybe

Summary: Model-based Analysis of ChIP-Seq data, MACS, which analyzes data generated by short read sequencers such as Solexa's Genome Analyzer. MACS empirically models the shift size of ChIP-Seq tags, and uses it to improve the spatial resolution of predicted binding sites. MACS also uses a dynamic Poisson distribution to effectively capture local biases in the genome, allowing for more robust predictions.

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Link: http://liulab.dfci.harvard.edu/MACS/ Category: ChIPseq