Bowtie
Revision as of 18:55, 28 April 2010 by Alperyilmaz (talk | contribs)
Application data |
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Created by | Ben Langmead, Cole Trapnell |
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Principal bioinformatics method(s) | Mapping, Burrows-Wheeler, FM-Index |
Created at | University of Maryland |
Maintained? | Maybe |
Input format(s) | FASTQ |
Output format(s) | SAM |
Operating system(s) | MacosX, Linux, Windows |
Summary: Bowtie is an ultrafast, memory-efficient short read aligner.
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Bowtie aligns short DNA sequences (reads) to the human genome at a rate of 25 million reads per hour on a typical workstation with 2 gigabytes of memory. Bowtie indexes the genome with a Burrows-Wheeler index to keep its memory footprint small: 1.3 GB for the human genome. It supports alignment policies equivalent to Maq and SOAP but is much faster: about 35x faster than Maq and over 350x faster than SOAP when aligning to the human genome.