NovelSeq

Application data
Biological application domain(s)	Structural variants - Novel sequence insertions
Principal bioinformatics method(s)	Mapping, Hard Clustering, Combinatorial Optimization, Assembly
Maintained?	Yes

Summary: A computational framework to discover the content and location of long novel sequence insertions using paired-end sequencing data

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Description

a computational framework to discover the content and location of long novel sequence insertions using paired-end sequencing data generated by the next-generation sequencing platforms. Our framework can be built as part of a general sequence analysis pipeline to discover multiple types of genetic variation (SNPs, structural variation, etc.), thus it requires significantly less computational resources than de novo sequence assembly.

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References

1. . 2010. Bioinformatics

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