NovelSeq

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Application data

Created by Iman Hajirasouliha, Fereydoun Hormozdiari, Can Alkan
Biological application domain(s) Structural variants, InDel discovery
Principal bioinformatics method(s) Mapping, Soft Clustering, Combinatorial Optimization, Assembly
Technology Illumina
Created at Simon Fraser University

University of Washington

Maintained? Yes
Input format(s) DIVET, SAM
Output format(s) FASTA
Programming language(s) C
Licence BSD License
Operating system(s) UNIX

Summary: A computational framework to discover the content and location of long novel sequence insertions using paired-end sequencing data

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Description

A computational framework to discover the content and location of long novel sequence insertions using paired-end sequencing data generated by the next-generation sequencing platforms. Our framework can be built as part of a general sequence analysis pipeline to discover multiple types of genetic variation (SNPs, structural variation, etc.), thus it requires significantly less computational resources than de novo sequence assembly.




Links


References

  1. . 2010. Bioinformatics


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