BEAP

Application data
Principal bioinformatics method(s)	Read mapping
Created at	Iowa State University
Maintained?	Maybe

Summary: The Blast Extension and Assembly Program (BEAP) uses a short starting DNA fragment to recursively blast nucleotide databases to obtain all sequences that overlaps to construct the a "full length" sequence.

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The Blast Extension and Assembly Program (BEAP) uses a short starting DNA fragment, often a EST or partial gene segment, as "primer", to recursively blast nucleotide databases in an attempt to obtain all sequences that overlaps, directly or indirectly, with the "primer" therefore help to "extend" the length of the original sequence for constructing a "full length" sequence for functional analysis, or at least to obtain neighboring regions of the segment for SNP detection and linkage disequilibrium analysis. The confidence of assembling the resulting sequences is achieved by using a known genome, such as human genome, as a reference.