Btrim
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Application data |
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| Principal bioinformatics method(s) | Sequence trimming |
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| Created at | Yale University |
| Maintained? | Yes |
| Operating system(s) | Linux |
Summary: Btrim is a fast and lightweight software to trim adapters and low quality regions in reads.
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Description
Btrim is a fast and lightweight software to trim adapters and low quality regions in reads from ultra high-throughput next-generation sequencing machines. It also can reliably identify barcodes and assign the reads to the original samples. Based on a modified Myers's bit-vector dynamic programming algorithm, Btrim can handle indels in adapters and barcodes. It removes low quality regions and trims off adapters at both or either end of the reads. A typical trimming of 30 M reads with two sets of adapter pairs can be done in about a minute with a small memory footprint. Btrim is a versatile stand-alone tool that can be used as the first step in virtually all next-generation sequence analysis pipelines.
Links
References
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| Web Search | Wiki Sites | Scientific |
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