Coral
Application data |
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Created by | L. Salmela |
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Principal bioinformatics method(s) | Sequence error correction |
Created at | University of Helsinki |
Maintained? | Yes |
Input format(s) | FASTA, FASTQ |
Output format(s) | FASTA, FASTQ |
Programming language(s) | C++ |
Summary: Corrects sequencing errors in short read data via multiple alignments
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Description
Coral corrects sequencing errors by forming multiple alignments. Unlike previous tools for error correction, Coral can utilize also bases distant from the error in the correction process because the whole read is present in the alignment. Coral is easily adjustable to reads produced by different sequencing technologies like Illumina Genome Analyzer and Roche/454 Life Sciences sequencing platforms because the sequencing error model can be defined by the user.
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References
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