DeFuse

Application data
Biological application domain(s)	Gene structure, RNA-Seq
Maintained?	Yes
Input format(s)	FASTQ

Summary: deFuse is a software package for gene fusion discovery using RNA-Seq data. The software uses clusters of discordant paired end alignments to inform a split read alignment analysis for finding fusion boundaries. The software also employs a number of heuristic filters in an attempt to reduce the number of false positives and produces a fully annotated output for each predicted fusion

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Links

• DeFuse Homepage [ edit link ]

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References

1. . 2011. PLoS Computational Biology

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