FACS
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Application data |
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| Created by | Henrik Stranneheim |
|---|---|
| Biological application domain(s) | Metagenomics |
| Technology | Any |
| Created at | KTH - Royal Institute of Technology |
| Maintained? | Yes |
| Input format(s) | FASTA |
| Output format(s) | FASTA |
| Programming language(s) | Perl, f |
| Licence | GPLv2 |
| Operating system(s) | Linux |
Summary: Rapid and accurate classification of sequences as belonging or not belonging to a reference sequence.
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A novel algorithm, FACS (Fast and Accurate Classification of Sequences), is introduced that can accurately and rapidly align sequences to a reference sequence. FACS was first optimized and validated using a synthetic metagenome dataset. An experimental metagenome dataset was then used to show that FACS is at least three times faster and more accurate than BLAT and SSAHA2 in classifying sequences when using references larger than 50Mbp.
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