HI
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Application data |
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| Created by | Quan Long |
|---|---|
| Principal bioinformatics method(s) | Haplotype reconstruction |
| Technology | Illumina |
| Created at | Sanger Institute |
| Maintained? | No |
| Input format(s) | FASTQ, CIGAR |
| Output format(s) | TXT |
| Programming language(s) | Java |
Summary: Program for haplotype reconstruction from paired-end reads.
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HI (Haplotype Improver) is a tool written in Java to improve the haplotype reconstructions of existing phasing tools.
The time complexity of this algorithm is linear to the number of reads and the space complexity is linear to the sum of heterozygotes of all individuals. Comparing with the time consuming sampling process of phasing tools, the time overhead added by HI is a small proportion affordable for the phasing tool users. At the same time, if the user can run phasing tools, her/his RAM can afford HI.
Links
- HI Homepage [ edit link ]
References
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