Illuminator
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Application data |
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| Biological application domain(s) | SNP detection, Indel detection |
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| Technology | Illumina |
| Maintained? | Yes |
Summary: Software for machines running Windows to identify variants in Illumina short read data.
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Description
Illuminator is a new sequence alignment program for the output from Illumina GA-II clonal sequencers. It is aimed primarily at kilobase-sized reference regions, as would typically be used in the context of mutation detection.
Illuminator can map 5 million index-tagged 36-nt reads in under 2 minutes on a standard desktop computer. It uses an algorithm that indexes the reference sequence as a series of 8-mers and then matches the genomic reads to the 8-mer index, in a mutation-tolerant way permitting identification of single-nucleotide substitutions and indels.
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References
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| Web Search | Wiki Sites | Scientific |
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