Knime4Bio
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Application data |
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| Created by | Pierre Lindenbaum |
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| Biological application domain(s) | Genomics, Gene regulation, Transcription factors and regulatory sites |
| Principal bioinformatics method(s) | Data retrieval |
| Created at | UMR 915, Institut du Thorax, Université of Nantes, 44000 Nantes, France |
| Maintained? | Yes |
| Input format(s) | VCF, Delimited Text |
| Output format(s) | Various |
| Software features | KNIME |
| Programming language(s) | Java |
| Software libraries | BigBed-java, BigWig-java, Picard |
| Licence | GPLv3 |
| Operating system(s) | any |
Summary: custom nodes for the interpretation of Next Generation Sequencing data with KNIME.
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Description
Abstract:Analysing large amounts of data generated by next-generation sequencing (NGS) technologies is difficult for researchers or clinicians without computational skills. They are often compelled to delegate this task to computer biologists working with command line utilities. The availability of easy-to-use tools will become essential with the generalisation of NGS in research and diagnosis. It will enable investigators to handle much more of the analysis. Here, we describe Knime4Bio, a set of custom nodes for the KNIME (The Konstanz Information Miner) interactive graphical workbench, for the interpretation of large biological datasets. We demonstrate that this tool can be utilised to quickly retrieve previously published scientific findings.
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