MAQ

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Application data

Created by Heng Li
Biological application domain(s) Genomics, SNP detection
Principal bioinformatics method(s) Read mapping
Created at The Wellcome Trust Sanger Institute
Maintained? No
Input format(s) FASTA, FASTQ
Output format(s) Maq
Programming language(s) C++, Perl
Interface type(s) Command line
Resource type(s) Command-line tool
Licence GPL

Summary: Mapping and Assembly with Qualities (renamed from MAPASS2). Particularly designed for Illumina-Solexa 1G Genetic Analyzer, and has preliminary functions to handle ABI SOLiD data.

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MAQ has been superseded by other, faster mapping programs, such as BWA by the same author. However, it's still good for some things (SNP calling mainly) and as it's primarily an alignment tool. It also comes with some useful PERL scripts for format conversion etc. MAQ does not align reads with indels.

MAQ's nonstandard output format can be converted to SAM format with tools included in the SAMtools distribution.

Links


References

  1. . 2008. Genome Research


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