Mauve
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Application data |
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| Created by | Aaron Darling |
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| Biological application domain(s) | Genomics, Transcriptomics |
| Principal bioinformatics method(s) | Sequence alignment comparison, Visualisation, Sequence assembly validation |
| Technology | Any |
| Created at | University of Wisconsin-Madison, University of Queensland, University of California-Davis, University of Technology Sydney |
| Maintained? | Yes |
| Input format(s) | FASTA, Multi-FastA, GenBank |
| Output format(s) | XMFA |
| Programming language(s) | C++, Java |
| Interface type(s) | Desktop GUI |
| Licence | GPL |
| Operating system(s) | Mac OS X, Windows, Linux |
| Contact: | mauve-users@lists.sourceforge.net |
Summary: Mauve Genome Alignment software, for comparing two or more draft or finished genomes
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Description
Mauve can compute and interactively browse whole-genome alignments of two or more genomes. Genomes can be in draft contigs or finished form. For draft genomes, Mauve provides a module called Mauve Contig Mover that enables ordering and orientation of draft genome contigs.using a reference genome.
The Mauve alignment browser offers a display of sequence conservation throughout the genome, a map of genome rearrangements, and if GenBank annotation has been loaded, it will display annotated sequence features as well.
Mauve requires about 16 bytes of memory per nt to compute genome alignments. Alignments of two bacteria can be computed in a few minutes, drosophila in an hour or so, and mammalian genome alignments can be computed in a day or two provided a computer with adequate memory resources.
Mauve Assembly Metrics can compute standardized statistics to assess the quality of sequence assemblies or alignments
Links
References
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