MethMarker
Application data |
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Biological application domain(s) | Epigenomics, DNA methylation |
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Created at | MPII |
Maintained? | Yes |
Programming language(s) | Java |
Operating system(s) | Windows, Linux, Mac OS X, Solaris |
Summary: MethMarker facilitates the design of DNA methylation assays for COBRA, bisulfite SNuPE, bisulfite pyrosequencing, MethyLight and MSP. It also implements a systematic workflow for design, optimization and (computational) validation of DNA methylation biomarkers. This workflow starts from a preselected differentially methylated region (DMR) and results in an optimized DNA methylation assay that is ready to be tested in a large-scale clinical trial.
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