MuMRescueLite
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Application data |
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| Biological application domain(s) | Genomics, ChIP-seq |
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| Principal bioinformatics method(s) | Mapping |
| Created at | RIKEN Yokohama Institute |
| Maintained? | No |
| Programming language(s) | Python |
| Licence | MIT |
Summary: Probabilistically reincorporates multi-mapping tags into mapped short read data.
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Description
MuMRescueLite is the software that enable to use the tag sequencies of mapped to multiple loci to the genome, for the expression analysis. At the mapping of short sequence tags of CAGE or ChIP-seq to the genome, sequence tags that map to multiple genomic loci (multi-mapping tags or MuMs), are routinely omitted from further analysis, leading to experimental bias and reduced coverage. MuMRescueLite probabilistically reincorporates multi-mapping tags into mapped short read data with acceptable computational requirements.
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References
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