Readaligner

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Application data

Principal bioinformatics method(s) Read mapping
Created at University of Helsinki
Maintained? Maybe

Summary: A tool for mapping (short) DNA reads into reference sequences.

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Features

  • Align reads using either k-mismatches or k-errors (mismatches, insertions and deletions) model.
  • Algorithms are based on Burrows-Wheeler transform and backward backtracking.
  • Includes a novel data structure called the rotation index that finds alignments with higher number of mismatches in feasible time (but requires a larger index and fixed length query reads).

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References

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