RefCov

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Application data

Created by Todd Wylie
Biological application domain(s) Copy number estimation
Created at University of Washington
Maintained? No

Summary: WashU Reference Coverage tool for analyzing the depth, breadth, and topology of sequencing coverage

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The refcov software suite was written as a toolkit to provide multiple methods for analyzing nucleotide reference sequence coverage. As such, it does not answer a single question, but rather provides the ability to easily formulate and answer multiple analytical questions. Methods and support are provided for general depth-of-coverage statistics as well as per-base-position nucleotide frequencies of layered query sequences against a given reference sequence backbone.

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