SEECER
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Application data |
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| Created by | Le H, Schulz MH, Bar-Joseph Z |
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| Biological application domain(s) | RNA-Seq quantification |
| Principal bioinformatics method(s) | Sequence error correction |
| Technology | Illumina, 454, Ion Torrent, PacBio |
| Created at | Carnegie Mellon University |
| Maintained? | Yes |
| Input format(s) | FASTA, FASTQ |
| Output format(s) | FASTA |
| Software features | supports multicore processors |
| Programming language(s) | C |
Summary: Sequence error correction for RNA-Seq data
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SEECER is an error correction method that removes errors that are introduced during sequencing. Mismatches, insertion or deletions are removed by creating multiple alignments of reads and building HMMs that are used to decide which reads are be corrected. In the provided reference it is shown that error correction with SEECER improves the downstream analysis, especially RNA de novo assembly.
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