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SEECER

3 bytes added, 00:16, 11 May 2013
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|sw summary=Error correction for RNA-Seq data
|bio domain=RNA Seq analysis
|bio tech=Illumina, 454, IonTorrentIon Torrent, PacBio,
|created by=Le H, Schulz MH, Bar-Joseph Z
|created at=Carnegie Mellon University
|maintained=Yes
|input format=FastaFASTA, FASTQ, Fastq
|output format=Fasta
|sw feature=supports multicore processors
|language=C
}}
 
SEECER is an error correction method that removes errors that are introduced during sequencing. Mismatches, insertion or deletions are removed by creating multiple alignments of reads and building HMMs that are used to decide which reads are be corrected. In the provided reference it is shown that error correction with SEECER improves the downstream analysis, especially RNA de novo assembly.
 
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