19930550
This reference describes Crossbow.
| PMID | PMID 19930550 |
|---|---|
| Title | Searching for SNPs with cloud computing. |
| Year | 2009 |
| Journal | Genome Biology |
| Author | Langmead B, Schatz MC, Lin J, Pop M, Salzberg SL. |
| Volume | 10 |
| Start page |
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Full text description
As DNA sequencing outpaces improvements in computer speed, there is a critical need to accelerate tasks like alignment and SNP calling. Crossbow is a cloud-computing software tool that combines the aligner Bowtie and the SNP caller SOAPsnp. Executing in parallel using Hadoop, Crossbow analyzes data comprising 38-fold coverage of the human genome in three hours using a 320-CPU cluster rented from a cloud computing service for about $85. Crossbow is available from http://bowtie-bio.sourceforge.net/crossbow/.
