AGE
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Application data |
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| Biological application domain(s) | Structural variation |
|---|---|
| Principal bioinformatics method(s) | Sequence alignment |
| Technology | Illumina |
| Created at | Yale Univeristy |
| Maintained? | Maybe |
| Licence | Creative Commons license (Attribution-NonCommerical). |
Summary: AGE is a tool that implements an algorithm for optimal alignment of sequences with SVs.
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Description
AGE stands for Sequence alignment with Gap Excision, AGE finds the optimal solution by simultaneously aligning the 5' and 3' ends of two given sequences and introducing a 'large-gap jump' between the local end alignments to maximize the total alignment score. AGE also works on tandem duplications, inversions and complex events involving two large gaps.
Links
References
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