BRAT
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Application data |
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| Biological application domain(s) | Epigenomics, DNA methylation |
|---|---|
| Principal bioinformatics method(s) | Bisulfite mapping, Mapping |
| Technology | Illumina |
| Maintained? | Maybe |
| Licence | GPLv3 |
Summary: accurate and efficient tool for mapping short reads obtained from the Illumina Genome Analyzer following sodium bisulfite conversion. Both single and paired ends are supported.
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We present a new, accurate and efficient tool for mapping short reads obtained from the Illumina Genome Analyzer following sodium bisulfite conversion. Our tool, BRAT, supports single and paired-end reads and handles input files containing reads and mates of different lengths. BRAT is faster, maps more unique paired-end reads and has higher accuracy than existing programs. The software package includes tools to end-trim low quality bases of the reads and to report nucleotide counts for mapped reads on the reference genome.
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