CABOG

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Application data

Biological application domain(s) Sequence assembly (de novo assembly)
Principal bioinformatics method(s) Sequence assembly
Technology Sanger, 454, Illumina
Created at The J. Craig Venter Institute
Maintained? Yes
Input format(s) FASTA, QUAL, SFF, AFG, Trace Archive
Software features Robust to homopolymer run length
Operating system(s) Linux

Summary: Celera Assembler is scientific software for DNA research.

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CA is a 'whole genome shotgun sequence assembler' -- it reconstructs long sequences of genomic DNA given the fragmentary data produced by whole-genome shotgun sequencing. Celera Assembler was modified for combinations of ABI 3730 and 454 FLX reads. The revised pipeline called CABOG (Celera Assembler with the Best Overlap Graph) is robust to homopolymer run length uncertainty, high read coverage, and heterogeneous read lengths.

Example of CA specfiles

Links


References

  1. . 2008. Bioinformatics


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