CEQer
|
Application data |
|
| Created by | Piazza Rocco |
|---|---|
| Biological application domain(s) | Exome analysis, Copy number estimation, Genetic variation analysis |
| Technology | Any |
| Created at | University of Milano-Bicocca |
| Maintained? | Yes |
| Input format(s) | SAM/BAM, Pileup |
| Output format(s) | Graphical |
| Software features | Copy number and allelic imbalance analyses from matched exomes. |
| Programming language(s) | C# |
| Interface type(s) | Command line |
| Resource type(s) | Command-line tool |
| Licence | GPLv3 |
| Operating system(s) | Windows, Mac, Linux |
| Contact: | rocco.piazza@unimib.it |
Summary: CEQer (Comparative Exome Quantification analyzer) is a graphical, event-driven tool for copy number abnormalities/allelic-imbalance coupled analysis of whole-exome sequencing data. By using case-control matched exome data, CEQer performs a comparative digital exonic quantification to generate CNA data and couples this information with exome-wide LOH and allelic imbalance detection. 200px|right
"Error: no local variable "counter" was set." is not a number.
Description
Copy number alterations (CNA) are common events occurring in leukaemias and solid tumors. Comparative Genome Hybridization (CGH) is actually the gold standard technique to analyze CNAs; however, CGH analysis requires dedicated instruments and is able to perform only low resolution Loss of Heterozygosity (LOH) analyses. CEQer (Comparative Exome Quantification analyzer) is a graphical, event-driven tool for CNA/allelic-imbalance (AI) coupled analysis of exome sequencing data. By using case-control matched exome data, CEQer performs a comparative digital exonic quantification to generate CNA data and couples this information with exome-wide LOH and allelic imbalance detection. This data is used to build mixed statistical/heuristic models allowing the identification of CNA/AI events.
Links
References
To add a reference for CEQer, enter the PubMed ID in the field below and click 'Add'.
Search for "CEQer" in the SEQanswers forum / BioStar or:
| Web Search | Wiki Sites | Scientific |
|---|---|---|
