Flexbar

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Application data

Biological application domain(s) Genomics
Principal bioinformatics method(s) Read pre-processing, DNA barcoding, Adapter removal, Sequence trimming, Quality control
Technology Illumina, 454, ABI SOLiD
Created at GitHub
Maintained? Yes
Input format(s) Fasta/q, Csfasta/q
Output format(s) Fasta/q, Csfasta/q
Software features Paired read support, separate barcode reads, multi-threading
Programming language(s) C++
Software libraries SeqAn, TBB
Licence GPLv3
Operating system(s) Linux, Windows, Mac OS X

Summary: Flexible barcode and adapter processing for next-generation sequencing platforms

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Description

Flexbar preprocesses high-throughput sequencing data efficiently. It demultiplexes barcoded runs and removes adapter sequences. Moreover, trimming and filtering features are provided. Flexbar increases mapping rates and improves genome and transcriptome assemblies. Next-generation sequencing data from Illumina, Roche 454, and the SOLiD platform is supported.


Links


References

  1. . 2012. Biology (Basel)


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