GPS
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Application data |
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| Created by | Guo Y, Papachristoudis G, Altshuler RC, Gerber GK, Jaakkola TS, Gifford DK, Mahony S |
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| Biological application domain(s) | Genomics, ChIP-seq, Transcription factors and regulatory sites, Epigenomics |
| Principal bioinformatics method(s) | Peak calling |
| Created at | Massachusetts Institute of Technology |
| Maintained? | Yes |
| Input format(s) | BED, SAM/BAM, Bowtie, ELAND |
| Software features | multi-threading |
| Programming language(s) | Java |
| Licence | Commercial, Freeware |
| Operating system(s) | Cross-Platform |
Summary: GPS is a high spatial resolution peak detection algorithm for ChIP-seq data.
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Description
The Genome Positioning System (GPS) is a software tool to study protein-DNA interaction using ChIP-seq data. GPS builds a probabilistic mixture model to predict the most likely positions of binding events. GPS predict binding events with high spatial resolution and is able to resolve closely spaced (less than 500bp) events that appear as a single cluster of reads.
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References
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