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{{Bioinformatics application
|sw summary=CNVkit is a software toolkit to infer and visualize copy number from targeted DNA sequencing data. It is designed for use with hybrid capture, including both whole-exome and custom target panels, and short-read sequencing platforms such as Illumina.|bio domain=Copy number estimation, Structural variation,|bio method=Structural variation discovery, Variant calling, Somatic variant calling,
|bio tech=Illumina,
|created by=Talevich E
== Description ==
<!-- Describe the application in the space below -->
CNVkit is a software toolkit to infer and visualize copy number from targeted DNA sequencing data. It is designed for use with hybrid capture, including both whole-exome and custom target panels, and short-read sequencing platforms such as Illumina.
This method uses the nonspecifically captured off-target reads to supplement read depth information from on-target regions. With relatively simple normalization steps to make these read depths comparable across the genome, CNVkit can produce copy ratio estimates extremely close to those by array CGH.
