BigBWA

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Application data

Created by Abuin JM, Pichel JC, Pena TF, Amigo J
Biological application domain(s) Genomics, Resequencing, Exome capture, Whole genome resequencing, Sequencing, Whole genome resequencing, Exome, Exome analysis, Exome and whole genome variant detection
Principal bioinformatics method(s) Read mapping, Mapping, Mapping, Sequence alignment
Technology Illumina, ABI SOLiD, SOLiD, Ion Torrent, Ion proton
Created at Universidade de Santiago de Compostela
Maintained? Yes
Input format(s) FASTQ, FASTA, BAM
Output format(s) SAM/BAM
Software version 0.1
Software features Gapped alignment, paired-end mapping
Programming language(s) Java
Software libraries BWA
Licence GPLv3
Operating system(s) Linux 64
Contact: josemanuel.abuin@usc.es

Summary: Tool to run the Burrows-Wheeler Aligner-BWA on a Hadoop cluster. It supports the algorithms BWA-MEM, BWA-ALN, and BWA-SW, working with paired and single reads. It implies an important reduction in the computational time when running in a Hadoop cluster, adding scalability and fault-tolerancy.

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Description

Approaching the Burrows-Wheeler Aligner to Big Data Technologies

BigBWA is a tool to run the Burrows-Wheeler Aligner (BWA) on a Hadoop cluster. The current version of BigBWA (v0.1, march 2015) supports the following BWA algorithms:

  • BWA-MEM
  • BWA-ALN
  • BWA-SW

All of them work with paired and single reads.

Links


References

  1. . 2015. Bioinformatics


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