Difference between revisions of "BBSeq"
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Latest revision as of 16:49, 2 December 2015
Application data |
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Biological application domain(s) | RNA-Seq quantification |
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Maintained? | Maybe |
Programming language(s) | R |
Summary: Tool for analyzing RNA-Seq data to analyze gene expression
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Description
BBSeq incorporates two approaches: (i) a simple beta-binomial generalized linear model, which has not been extensively tested for RNA-Seq data, and (ii) an extension of an expression mean-variance modeling approach to RNA-Seq data, involving modeling of the overdispersion as a function of the mean. The approaches are flexible, allowing for general handling of discrete experimental factors and continuous covariates.
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